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Gamma-Aminobuttersäure (GABA) ist eine nicht-proteinogene Aminosäure mit vier Kohlenstoffen, die in Bakterien, Pflanzen und Wirbeltieren vorkommt. Ursprünglich wurde sie in Pflanzen entdeckt (Steward et al., 1949), dann im Gehirn von Säugetieren (Roberts und Frankel, 1950) und später in Tieren (Roberts und Eidelberg, 1960) und mehreren anderen Organismen, einschließlich Bakterien und Pilzen (Bouche et al., 2003). In Wirbeltieren wird es durch die irreversible α-Decarboxylierungsreaktion von L-Glutaminsäure oder ihren Salzen gebildet, die durch das Enzym Glutaminsäure-Decarboxylase katalysiert wird (Satya Narayan und Nair, 1990), und fungiert als hemmender Neurotransmitter im zentralen Nervensystem (ZNS) (Roberts und Frankel, 1950; Petroff, 2002). GABA ist von entscheidender Bedeutung für das Funktionieren des ZNS, in dem etwa 60-75 % aller Synapsen GABA-ergen sind (Schwartz, 1988). https://svetka.info/gaba-neurotransmetteur-avis-francais.html Gamma-Aminobuttersäure (GABA) ist ein wichtiger Neurotransmitter, der einen Großteil unserer Gehirnfunktionen reguliert. Bisher dachte man, dass mit der Nahrung aufgenommene GABA die Blut-Hirn-Schranke nicht überwinden kann, aber neue Forschungsergebnisse deuten darauf hin, dass dies doch möglich ist.

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